| i 4 N i | Mermaid | 1995 |
| I Abandoned My Engagement Because My Sister Is a Tragic Heroine, But Somehow I Became Entangled with a Righteous Prince | Seven Seas | 2024 |
| I Abandoned My Engagement Because My Sister Is a Tragic Heroine, But Somehow I Became Entangled With a Righteous Prince (Light Novel) | Seven Seas | 2025 |
| I Am a Barbarian (Cedar Run) | Cedar Run | 2022 |
| I Am a Cat Barista | Seven Seas | 2022 |
| I Am a Cat: The Manga Edition (Soseki Natsume’s…) | Tuttle | 2021 |
| I Am A Hero | Dark Horse | 2016, 2018 |
| I Am A Hero (Carlsen Manga) | Carlsen Manga | 2012 |
| I Am A Hero (Shogakukan) | Shogakukan | 2009 |
| I Am Alice: Body Swap In Wonderland | Seven Seas | 2014-2015 |
| I Am An Avenger | Marvel | 2010–2011 |
| I Am a Number | IDW | 2017 |
| I Am Batman | DC | 2021-2023 |
| I Am Billie Jean King | Dial Books | 2019 |
| I Am Blue, in Pain, and Fragile | Seven Seas | 2022 |
| I Am Captain America | Marvel | 2011-2012 |
| I Am Coyote | Eclipse | 1984 |
| I am Gandhi (Dial Books) | Dial | 2018 |
| I Am Going to Be Small (Jeffrey Brown) | Jeffrey Brown | 2002 |
| I Am Groot | Marvel | 2017 |
| I Am Here | Kodansha | 2010, 2012 |
| I am Hermes! | Holiday House | 2019 |
| I Am Hexed | Rocketship | 2023 |
| I Am Iron Man | Marvel | 2023 |
| I Am Legend | Eclipse | |
| I Am Legend—Awakening | Vertigo | 2007 |
| I Am Legion | Humanoids | 2004, 2017 |
| I Am Legion (Devil’s Due) | Devil’s Due | 2009 |
| I Am Not a Succubus | Ghost Ship | 2022 |
| "I Am Not a Televangelist!": The Continuing Saga of Reverend Will B. Dunn | Longstreet | 1988 |
| I Am Not OK With This | Fantagraphics | 2017 |
| I Am Not Real | Stone Church | 2024 |
| I Am Not Starfire | DC | 2021 |
| I Am Not Your Maid | Project H | 2014-2015 |
| I Am Only a Foreigner Because You Do Not Understand | Secret Acres | 2023 |
| I Am Space Dandy | Kodansha | 2016 |
| I am Spartacus | Cellar Door | 2006 |
| I Am Stan: A Graphic Biography of the Legendary Stan Lee | Ten Speed | 2023 |
| I Am Their Silence | Dark Horse | 2026 |
| I Am the Law | Rebellion | 2025 |
| I Am the Law: How Judge Dredd Predicted Our Future | Rebellion | 2022 |
| I Am Trying to Love You | Floating World | 2023 |
| I Ate the Whole World to Find You | Drawn & Quarterly | 2025 |
| Ibaraki and Friends | Z2 | 2022 |
| I Beat Things with My Face! | Still Ill Princess | |
| I Before E | Fantagraphics | 1991, 1994 |
| I Beg Your Pardon | Image | 2009 |
| I Belong to the Baddest Girl at School | One Peace | 2021 |
| Iber | Federazione Italiana Editori Giornali | 1975 |
| Ibis the Invincible | Fawcett | 1943-1948 |
| I•Bots (Isaac Asimov’s…, 1st Series) | Tekno | 1995-1996 |
| I•Bots (Isaac Asimov’s…, 2nd Series) | Big | 1996-1997 |
| I•Bots: History of I•Botics—The Illustrated Novel (Isaac Asimov’s…) | HarperCollins | 1997 |
| I Breathed a Body | AfterShock | 2021 |
| iCandy | DC | 2003-2004 |
| I Cannot Reach You | Yen | 2021 |
| I Can Read Comics | Harper Alley | 2021 |
| I Can Read Comics: Ty’s Travels: Camp-Out | Harper Alley | 2023 |
| I Can See You Comin’! | Eurotica | 1999 |
| I Can Sell You a Body | IDW | 2019-2020 |
| I Can’t Believe I Slept With You | Seven Seas | 2022 |
| I Can’t Get Through the Night Alone | Tokyopop/Love X Love | 2025 |
| I Can’t Refuse S | Steamship | 2023 |
| I Can’t Say No to the Lonely Girl | Kodansha | 2024 |
| I Can’t Stand Being Your Childhood Friend | Seven Seas | 2025 |
| I Can’t Stop Loving You! | Kitty | 2006 |
| Icaro | IBooks | 2003-2004 |
| Icarus | Comicmix | 2016 |
| Icarus (Aircel) | Aircel | 1987 |
| Icarus (Kardia) | Kardia | 1992 |
| Icarus and Jellinek | Silence in the Library | |
| I.C.E. | 12-Gauge | 2011–2012 |
| Ice Age Comics | The Print Mint | 1974 |
| Ice Age: Continental Drift | Boom! | 2012 |
| Ice Age: Iced In | Boom! | 2011 |
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