| Z | Keystone | 1994-1995 |
| Z1 | Zeleznik Illustration | 2003 |
| Zabime Sisters, The | :01 First Second | 2010 |
| Zachary Holmes: Case One: The Monster | Dark Horse | 2002 |
| Zachary Holmes: Case Two: The Sorcerer | Dark Horse | 2002 |
| Zack (Koralle) | Koralle | 1972-1980 |
| Zack (Mosaik) | Mosaik | 1999-2010 |
| Zack Comic Box | Koralle | 1972-1981 |
| Zack, The Zombie Exterminator | Coffin | 2015-2016 |
| Zadar the Savage | Darkside Media | 2022 |
| Zago | Fox | 1948-1949 |
| Zagor | Daim | 1965-2019, 2026 |
| Zagor (Ediciones Zinco) | Ediciones Zinco | 1982-1984 |
| Zagor (Epicenter) | Epicenter | 2015-2019 |
| Zagor (Slobodna Dalmacija) | Slobodna Dalmacija | 1994-2001 |
| Zagor (Vecchi) | Editora Vecchi | 1978-1983 |
| Zagor: 1000 Faces of Fear | Epicenter | 2017 |
| Zagor Collana Lampo | Sergio Bonelli Editore | 1961 |
| Zagor Extra | Slobodna Dalmacija | 1996 |
| Zagor Gigante | Sergio Bonelli Editore | 1965 |
| Zagor: In the Jaws of Madness | Epicenter | 2019 |
| Zagor Kolor Biblioteka | Libellus | 2004 |
| Zagor Più | Sergio Bonelli | 2021-2025 |
| Zagor: Shadow of the Vampire | Epicenter | 2022 |
| Zagor: Terror from the Sea | Epicenter | 2015 |
| Zagor: The Alien Saga | Epicenter | 2019 |
| Zagor: The Forest of Crossed Destinies | Epicenter | 2025 |
| Zagor: The Great Conspiracy | Epicenter | 2021 |
| Zagor: The Lost Mine | Epicenter | 2022 |
| Zagor: The Lost World | Epicenter | 2018 |
| Zagor: The Northwest Passage | Epicenter | 2025 |
| Zagor: The Origins | Epicenter | 2018 |
| Zagor: The Red Sand | Epicenter | 2016 |
| Zagor: The Return of Cain | Epicenter | 2023 |
| Zagor: The Scepter of the Tin Hinan | Epicenter | 2023 |
| Zagor Vs. Supermike | Epicenter | 2017 |
| Zagor: Voodoo Vendetta | Epicenter | 2016 |
| Zagor Zombies in Darkwood Signature Edition | Epicenter | 2025 |
| Zahn | Class | 2008 |
| Zaibatsu Tears | Limelight | 1997-1998 |
| Zaibatsu Tears (Vol. 2) | Limelight | 1995 |
| Zakimort | Casa Editrice Astoria | 1965-1973 |
| Zaks and Other Lost Stories, The | Comicmix | 2023 |
| Zam (Zap Jam) | Print Mint | 1974 |
| Zam Zap Jam | Print Mint | 1974 |
| Zandar The Savage | Darkside Media | 2022 |
| Zane & Tyler | Boy Meert Hero | 2011 |
| Zap Comix | Last Gasp | 1967-1988, 2019 |
| Zapper, The | Edwin Lopez | 2022 |
| Zappeurs—Hors série, Les | Dupuis | 2005 |
| Zappeurs, Les | Dupuis | 1994 |
| Zapt! | Tokyopop | 2006-2007 |
| Zap To Zippy: The Impact of Underground Comix | Cartoon Art Museum | 1990 |
| Zara la Vampira (Elviberia) | Elviberia | 1976-1977 |
| Zara La Vampire | Elvifrance | 1975 |
| Zarjaz | Underfire | 2006, 2011 |
| Zarpa de Acero | Ediciones Surco | 1983-1983 |
| Zarpa de Acero (Vertice) | Ediciones Vertice | 1964-1965 |
| Zarpa de Acero Extra (Vertice) | Ediciones Vertice | 1966-1970 |
| Zarpa de Leon | Ediciones Toray | 1949-1951 |
| Zärtliche Violetta | Carlsen | 1982 |
| Zatanna | DC | 1993 |
| Zatanna (2nd Series) | DC | 2010–2011 |
| Zatanna (3rd Series) | DC | 2025 |
| Zatanna (4th Series) | DC | 2026 |
| Zatanna and the House of Secrets | DC | 2020 |
| Zatanna & The Ripper | DC | 2023-2024 |
| Zatanna: Bring Down the House | DC | 2024 |
| Zatanna by Paul Dini | DC | 2017, 2024 |
| Zatanna by Paul Dini Omnibus | DC | 2026 |
| Zatanna: Everyday Magic | Vertigo | 2003 |
| Zatanna Special | DC | 1987 |
| Zatanna: The Jewel of Gravesend | DC | 2022 |
| Zatch Bell! | Viz | 2005-2006, 2008 |
| Zaucer of Zilk, The | IDW | 2012-2013 |
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